Compound Detail

CHEMBL3397496

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CC(=O)N[C@H]1[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CNc2cccc(NC(=O)CCCCC3CCSS3)c2)O[C@H](CO)[C@H](OS(=O)(=O)[O-])[C@@H]1O[C@@H]1O[C@H](C(=O)[O-])[C@@H](O)[C@H](OS(=O)(=O)[O-])[C@H]1OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+]

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL3397496
Phase	Preclinical
Structure Type	MOL
InChI Key	BNLZKHDLVKTGGT-JHNPOLKLSA-J
Parent Compound	CHEMBL3559019
Active Moiety	CHEMBL3559019

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

Molecular Properties

1080.1

MW (Da)

Drug Information

Molecule Type	Small molecule
Availability	Unknown
Chirality	Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula	C34H49N3Na4O26S5
MW	1168.06

Activity Summary

Kd 1 meas. best 7.28

Target Activity Profile

Target	Type	Best pChEMBL	Mean pChEMBL	Best (nM)	# Data
Fibroblast growth factor 2 CHEMBL3107	Kd	7.28	7.28	52.0	1

Activity Data Samples

Top measurements by pChEMBL value

Target	Type	Rel.	Value	Units	pChEMBL	Assay	PubMed
Fibroblast growth factor 2	Kd	=	52.0	nM	7.28	Binding affinity to basic fibroblast growth factor (unknown origin) using sugar ...	25765912

Literature References

PubMed	DOI	Target Context	# Activities
25765912	10.1016/j.bmcl.2015.02.054	Fibroblast growth factor 2	1

Data from ChEMBL 36 via Core Engine