Compound Detail
CHEMBL340040
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Basic Information
| ChEMBL ID | CHEMBL340040 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ARPUGEZSWJIZMR-GHVJWSGMSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
424.4
MW (Da)
5.07
ALogP
7
HBA
3
HBD
128.8
PSA (Ų)
0.31
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Thrombopoietin receptor CHEMBL1864 | EC50 | 5.52 | 5.52 | 3000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Thrombopoietin receptor | EC50 | = | 3000.0 | nM | 5.52 | Effective concentration for thrombopoietin luciferase activity was determined in... | 11606138 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11606138 | 10.1021/jm010283l | Thrombopoietin receptor | 2 |
Data from ChEMBL 36 via Core Engine