Compound Detail
CHEMBL3410416
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3410416 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UGWKGZBFDXNOBE-IBGZPJMESA-N |
1
Targets
1
Activities
1
Assay Types
1
PK Parameters
5
Publications
0
Known Names
Molecular Properties
407.5
MW (Da)
2.97
ALogP
5
HBA
2
HBD
99.6
PSA (Ų)
0.70
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.24
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Respiratory syncytial virus CHEMBL612679 | EC50 | 7.24 | 7.24 | 57.0 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| Fu | 0.17 | - | Homo sapiens |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Respiratory syncytial virus | EC50 | = | 57.0 | nM | 7.24 | Antiviral activity against Respiratory syncytial virus A2 infected in human Hep2... | 25574686 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25574686 | 10.1021/jm5017768 | ADMET | 4 |
| 25574686 | 10.1021/jm5017768 | Respiratory syncytial virus | 1 |
| 25574686 | 10.1021/jm5017768 | No relevant target | 1 |
| 25574686 | 10.1021/jm5017768 | Plasma | 1 |
| 25574686 | 10.1021/jm5017768 | MT4 | 1 |
Data from ChEMBL 36 via Core Engine