Compound Detail
CHEMBL34170
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Basic Information
| ChEMBL ID | CHEMBL34170 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SFEBAZSWFKLMDP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
413.7
MW (Da)
4.27
ALogP
2
HBA
1
HBD
23.5
PSA (Ų)
0.71
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(1A) dopamine receptor CHEMBL265 | Ki | 8.77 | 8.77 | 1.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(1A) dopamine receptor | Ki | = | 1.71 | nM | 8.77 | In vitro binding affinity towards Dopamine receptor D1 by displacing [125I]FISCH... | 2525621 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2525621 | 10.1021/jm00127a005 | D(1A) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine