Compound Detail
CHEMBL34177
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Basic Information
| ChEMBL ID | CHEMBL34177 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MDIKUXJIYAVQRI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
501.3
MW (Da)
6.65
ALogP
4
HBA
1
HBD
76.7
PSA (Ų)
0.29
QED
2
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.95
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cysteinyl leukotriene receptor 1 CHEMBL5645 | Kd | 5.95 | 5.95 | 1130.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cysteinyl leukotriene receptor 1 | Kd | = | 1130.0 | nM | 5.95 | In vitro affinity for CysLT1 receptors on guinea pig lung membranes, measured by... | 9554876 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9554876 | 10.1021/jm970179x | Cysteinyl leukotriene receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine