Cysteinyl leukotriene receptor 1 · SINGLE PROTEIN · Cavia porcellus
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As of 2026-09-13Protein identity stays anchored to UniProt Q2NNR5. Use UniProt Q2NNR5 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q2NNR5 as the stable identity anchor, then attach disease evidence before program review.
Cysteinyl leukotriene receptor 1
Review this target as Cysteinyl leukotriene receptor 1, mapped to UniProt Q2NNR5. Sequence length is 340 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Cysteinyl leukotriene receptor 1 as ChEMBL target CHEMBL5645, mapped to UniProt Q2NNR5. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Cysteinyl leukotriene receptor 1 |
| Target Type | SINGLE PROTEIN |
| Organism | Cavia porcellus |
| UniProt | Q2NNR5 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Cysteinyl leukotriene receptor 1 |
| UniProt Accession | Q2NNR5 |
| Component Type | Protein |
| Sequence Length | 340 aa |
Cysteinyl leukotriene receptor 1
Review this target as Cysteinyl leukotriene receptor 1, mapped to UniProt Q2NNR5. Sequence length is 340 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL21333 | 10.36 | IC50 | 0.044 | Approved |
| CHEMBL47430 | 10.0 | Ki | 0.1 | Preclinical |
| CHEMBL46663 | 9.92 | Ki | 0.12 | Preclinical |
| CHEMBL275357 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL330649 | 9.7 | IC50 | 0.2 | Preclinical |
| CHEMBL15177 | 9.7 | Ki | 0.2 | Preclinical |
| CHEMBL99775 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL95234 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL124095 | 9.52 | IC50 | 0.3 | Preclinical |
| CHEMBL603 | 9.52 | Ki | 0.3 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 35 | 239 | 8.1 |
| single protein format | 26 | 89 | 7.6 |
| cell membrane format | 24 | 147 | 7.7 |
| assay format | 9 | 9 | 6.4 |
| organism-based format | 2 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| tissue-based format | 18 | 18 | 8.3 |
| assay format | 5 | 0 | — |
| cell-based format | 1 | 6 | 8.5 |
| organism-based format | 1 | 0 | — |