Compound Detail
CHEMBL343492
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Basic Information
| ChEMBL ID | CHEMBL343492 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BODASUORRGHPGV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
265.4
MW (Da)
3.26
ALogP
3
HBA
0
HBD
21.1
PSA (Ų)
0.72
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.85
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1D CHEMBL1983 | Ki | 8.85 | 8.85 | 1.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1D | Ki | = | 1.4 | nM | 8.85 | Displacement of [3H]5-HT from human 5-hydroxytryptamine 1D receptor expressed in... | 14643336 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14643336 | 10.1016/j.bmcl.2003.09.025 | 5-hydroxytryptamine receptor 1D | 3 |
Data from ChEMBL 36 via Core Engine