Compound Detail
CHEMBL34545
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Basic Information
| ChEMBL ID | CHEMBL34545 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NPLHCOQGSXYKRI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
337.8
MW (Da)
3.05
ALogP
4
HBA
0
HBD
53.0
PSA (Ų)
0.79
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| C8166 CHEMBL614533 | IC50 | 6.55 | 6.55 | 280.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| C8166 | IC50 | = | 280.0 | nM | 6.55 | Antiviral activity was evaluated by inhibition of HIV-1 replication in CD4+ lymp... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00257-T | C8166 | 3 |
Data from ChEMBL 36 via Core Engine