Compound Detail
CHEMBL346234
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Basic Information
| ChEMBL ID | CHEMBL346234 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HIKKUMIMNQGLJW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
409.6
MW (Da)
5.79
ALogP
4
HBA
1
HBD
60.2
PSA (Ų)
0.63
QED
1
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aromatase CHEMBL1978 | Ki | 7.75 | 7.75 | 18.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aromatase | Ki | = | 18.0 | nM | 7.75 | Evaluated for its competitive inhibitory activity against Cytochrome P450 19A1 w... | 3959033 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3959033 | 10.1021/jm00154a025 | Aromatase | 7 |
Data from ChEMBL 36 via Core Engine