Compound Detail
CHEMBL348107
ACRYLAMIDE Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL348107 |
| Name | ACRYLAMIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HRPVXLWXLXDGHG-UHFFFAOYSA-N |
1
Targets
3
Activities
2
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
71.1
MW (Da)
-0.34
ALogP
1
HBA
1
HBD
43.1
PSA (Ų)
0.42
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.03
Ki 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fibroblast growth factor receptor 4 CHEMBL3973 | IC50 | 6.03 | 6.03 | 938.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fibroblast growth factor receptor 4 | IC50 | = | 938.0 | nM | 6.03 | Inhibition of human N-terminal GST-tagged FGFR4 cytoplasmic domain (460 to 802 e... | 27914362 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2939242 | 10.1021/jm00155a005 | Alcohol dehydrogenase | 1 |
| 2939242 | 10.1021/jm00155a005 | No relevant target | 1 |
| 25137375 | 10.1021/jm500747h | Glyceraldehyde-3-phosphate dehydrogenase | 1 |
| 27914362 | 10.1016/j.ejmech.2016.11.052 | Fibroblast growth factor receptor 4 | 1 |
| 27996267 | 10.1021/acs.jmedchem.6b00788 | Sodium-dependent dopamine transporter | 1 |
| 32898762 | 10.1016/j.ejmech.2020.112740 | Glyceraldehyde-3-phosphate dehydrogenase | 1 |
Data from ChEMBL 36 via Core Engine