Compound Detail
CHEMBL349181
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Basic Information
| ChEMBL ID | CHEMBL349181 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNSBEPKGFVENFS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
189.9
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 CHEMBL3229 | IC50 | 4.17 | 4.17 | 68000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Fatty-acid amide hydrolase 1 | IC50 | = | 68000.0 | nM | 4.17 | Inhibition of Wistar rat brain FAAH assessed as [3H]arachidonoylethanolamide hyd... | 18983140 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11266183 | 10.1016/s0960-894x(01)00056-7 | Prostaglandin E2 receptor EP3 subtype | 1 |
| 18983140 | 10.1021/jm801051t | Fatty-acid amide hydrolase 1 | 1 |
| 18983140 | 10.1021/jm801051t | Monoglyceride lipase | 1 |
Data from ChEMBL 36 via Core Engine