Compound Detail
CHEMBL349516
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Basic Information
| ChEMBL ID | CHEMBL349516 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HGTDLKXUWVKLQX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
152.0
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Autotaxin CHEMBL3691 | IC50 | 4.9 | 4.9 | 12589.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Autotaxin | IC50 | = | 12589.25 | nM | 4.9 | Inhibition of full length human C-terminal 6-His-tagged ATXbeta using FS-3 as su... | 28564542 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11266183 | 10.1016/s0960-894x(01)00056-7 | Prostaglandin E2 receptor EP3 subtype | 1 |
| 28564542 | 10.1021/acs.jmedchem.6b01224 | Autotaxin | 1 |
Data from ChEMBL 36 via Core Engine