Compound Detail
CHEMBL350705
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL350705 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DSAFEZWPXHHTBJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
343.5
MW (Da)
3.78
ALogP
3
HBA
0
HBD
41.3
PSA (Ų)
0.63
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Heart phosphodiesterase CHEMBL2111408 | IC50 | 4.47 | 4.47 | 34000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Heart phosphodiesterase | IC50 | = | 34000.0 | nM | 4.47 | Inhibition of cAMP phosphodiesterase in bovine heart | 6265639 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6265639 | 10.1021/jm00138a027 | Heart phosphodiesterase | 2 |
Data from ChEMBL 36 via Core Engine