Compound Detail
CHEMBL350972
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Basic Information
| ChEMBL ID | CHEMBL350972 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OYMSVEYECKLFKC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
285.4
MW (Da)
2.12
ALogP
5
HBA
0
HBD
46.8
PSA (Ų)
0.79
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serotonin 3 (5-HT3) receptor CHEMBL2094116 | IC50 | 7.55 | 7.55 | 28.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serotonin 3 (5-HT3) receptor | IC50 | = | 28.0 | nM | 7.55 | Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 3 receptor | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)80182-7 | Serotonin 3 (5-HT3) receptor | 2 |
| - | 10.1016/S0960-894X(01)80182-7 | 5-hydroxytryptamine receptor 1A | 1 |
| - | 10.1016/S0960-894X(01)80182-7 | Serotonin 2 (5-HT2) receptor | 1 |
| - | 10.1016/S0960-894X(01)80182-7 | D(2) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine