Compound Detail
CHEMBL352015
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Basic Information
| ChEMBL ID | CHEMBL352015 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GIGYKXHGYNZBEN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
266.3
MW (Da)
4.47
ALogP
2
HBA
2
HBD
40.5
PSA (Ų)
0.84
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| MCF7S CHEMBL614328 | EC50 | 6.89 | 6.89 | 130.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| MCF7S | EC50 | = | 130.0 | nM | 6.89 | Agonist activity against MCF-7 cell proliferation | 1738150 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1738150 | 10.1021/jm00081a021 | MCF7S | 6 |
| 1738150 | 10.1021/jm00081a021 | Estrogen receptor | 2 |
| 1738150 | 10.1021/jm00081a021 | Protein kinase C, PKC; classical | 2 |
| 1738150 | 10.1021/jm00081a021 | BT-20 | 2 |
| 1738150 | 10.1021/jm00081a021 | Unchecked | 1 |
| 16610793 | 10.1021/jm0512037 | Steroid hormone receptor ERR1 | 1 |
| 16610793 | 10.1021/jm0512037 | Steroid hormone receptor ERR2 | 1 |
| 16610793 | 10.1021/jm0512037 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine