Compound Detail
CHEMBL352490
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL352490 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KRYVEVPMULIYPV-QAQDUYKDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
327.5
MW (Da)
2.99
ALogP
3
HBA
1
HBD
35.6
PSA (Ų)
0.91
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.39
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Nociceptin receptor CHEMBL4503 | Ki | 7.39 | 7.39 | 41.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Nociceptin receptor | Ki | = | 41.0 | nM | 7.39 | Inhibition against binding of radioligand [leucyl-3H]-OFQ to membrane of human e... | 10782696 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10782696 | 10.1016/s0960-894x(00)00111-6 | Unchecked | 2 |
| 10782696 | 10.1016/s0960-894x(00)00111-6 | Nociceptin receptor | 1 |
| 10782696 | 10.1016/s0960-894x(00)00111-6 | Mu-type opioid receptor | 1 |
| 10782696 | 10.1016/s0960-894x(00)00111-6 | Kappa-type opioid receptor | 1 |
| 10782696 | 10.1016/s0960-894x(00)00111-6 | Delta-type opioid receptor | 1 |
Data from ChEMBL 36 via Core Engine