Compound Detail
CHEMBL355185
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Basic Information
| ChEMBL ID | CHEMBL355185 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MEOPUGZDBPCXEQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
361.4
MW (Da)
4.43
ALogP
3
HBA
1
HBD
59.2
PSA (Ų)
0.52
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GH3 CHEMBL614571 | EC50 | 6.68 | 6.68 | 207.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| GH3 | EC50 | = | 207.0 | nM | 6.68 | Concentration required for enhancing calcium influx into GH 3 cells was determin... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00132-D | GH3 | 6 |
| 8151623 | 10.1021/jm00033a014 | No relevant target | 1 |
| 8151623 | 10.1021/jm00033a014 | ADMET | 1 |
| 8151623 | 10.1021/jm00033a014 | Cavia porcellus | 1 |
Data from ChEMBL 36 via Core Engine