Compound Detail
CHEMBL3559600
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3559600 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QXDCQICQQSQQFK-UHFFFAOYSA-O |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
322.5
MW (Da)
2.48
ALogP
4
HBA
2
HBD
64.3
PSA (Ų)
0.37
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 7.13
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cyclic nucleotide-gated channel alpha-1 CHEMBL4907 | Kd | 7.13 | 6.49 | 74.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cyclic nucleotide-gated channel alpha-1 | Kd | = | 74.0 | nM | 7.13 | Apparent dissociation constant against Cyclic nucleotide gated channel alpha 1 a... | 16134947 |
| Cyclic nucleotide-gated channel alpha-1 | Kd | = | 1400.0 | nM | 5.85 | Apparent dissociation constant against Cyclic nucleotide gated channel alpha 1 a... | 16134947 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16134947 | 10.1021/jm0502485 | Cyclic nucleotide-gated channel alpha-1 | 2 |
Data from ChEMBL 36 via Core Engine