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Compound Detail

CHEMBL3560781

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O=C(Nc1ccc(CCN2CCCCC2)cc1)c1cccc(OCc2ccccc2)c1

Basic Information

ChEMBL ID CHEMBL3560781
Phase Preclinical
Structure Type MOL
InChI Key KWNJCSHGOMXDKG-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

414.6
MW (Da)
5.55
ALogP
3
HBA
1
HBD
41.6
PSA (Ų)
0.53
QED
1
Ro5 Violations
8
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H30N2O2
MW 414.55
Aromatic Rings 3
Heavy Atoms 31
NP-Likeness -1.32

Activity Summary

IC50 2 meas. best 5.64

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 5.64 4.84 2300.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine