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Compound Detail

CHEMBL3582004

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CCC(C)C(=O)O[C@@]12[C@H](OC(C)=O)[C@@H](C)[C@]3(O)[C@@H]4C=C(C)C(=O)[C@@H]4CC(CO)=C[C@H]3[C@@H]1C2(C)C

Basic Information

ChEMBL ID CHEMBL3582004
Phase Preclinical
Structure Type MOL
InChI Key VLQRBYYAEZBEJX-IXSMXENYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

474.6
MW (Da)
2.98
ALogP
7
HBA
2
HBD
110.1
PSA (Ų)
0.47
QED
0
Ro5 Violations
5
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C27H38O7
MW 474.59
Aromatic Rings 0
Heavy Atoms 34
NP-Likeness 3.12

Activity Summary

EC50 2 meas. best 4.89

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Human immunodeficiency virus 2
CHEMBL380
EC50 4.89 4.89 13000.0 1
NON-PROTEIN TARGET
CHEMBL3879801
EC50 4.11 4.11 77000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

Data from ChEMBL 36 via Core Engine