Compound Detail
CHEMBL3582305
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3582305 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AXBANCDWRYXEBP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
413.4
MW (Da)
2.82
ALogP
7
HBA
1
HBD
98.0
PSA (Ų)
0.49
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatocyte growth factor receptor CHEMBL3717 | IC50 | 9.89 | 9.89 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatocyte growth factor receptor | IC50 | = | 0.13 | nM | 9.89 | Inhibition of C-Met (unknown origin) using polu (Glu,Tyr)4:1 substrate after 30 ... | 26005523 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26005523 | 10.1021/ml5004876 | Hepatocyte growth factor receptor | 1 |
Data from ChEMBL 36 via Core Engine