Compound Detail
CHEMBL358640
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Basic Information
| ChEMBL ID | CHEMBL358640 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KPQSZJRCWYCLHO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
259.3
MW (Da)
2.93
ALogP
5
HBA
1
HBD
63.3
PSA (Ų)
0.68
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.51
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Macrophage migration inhibitory factor CHEMBL2085 | Ki | 5.51 | 5.51 | 3100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Macrophage migration inhibitory factor | Ki | = | 3100.0 | nM | 5.51 | Inhibitory activity against tautomerase macrophage migration inhibitory factor (... | 11170644 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11170644 | 10.1021/jm000386o | Macrophage migration inhibitory factor | 1 |
Data from ChEMBL 36 via Core Engine