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Compound Detail

CHEMBL359278

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CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)N[C@H](C)CC

Basic Information

ChEMBL ID CHEMBL359278
Phase Preclinical
Structure Type MOL
InChI Key FSBHLSINBYYIIF-PZSIIWHGSA-N
2
Targets
5
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

359.6
MW (Da)
7.05
ALogP
1
HBA
1
HBD
29.1
PSA (Ų)
0.23
QED
1
Ro5 Violations
16
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C24H41NO
MW 359.60
Aromatic Rings 0
Heavy Atoms 26
NP-Likeness 0.30

Activity Summary

Ki 5 meas. best 7.13

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Cannabinoid receptor 1
CHEMBL3571
Ki 7.13 6.93 73.6 4
Cannabinoid receptor 2
CHEMBL5373
Ki 5.88 5.88 1330.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
9876105 10.1021/jm970257g Cannabinoid receptor 1 2
10072686 10.1021/jm980461j Fatty-acid amide hydrolase 1 2
9876105 10.1021/jm970257g Cannabinoid receptor 2 1
10072686 10.1021/jm980461j Cannabinoid receptor 1 1
9057852 10.1021/jm960752x Cannabinoid receptor 1 1

Data from ChEMBL 36 via Core Engine