Compound Detail
CHEMBL3605509
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Basic Information
| ChEMBL ID | CHEMBL3605509 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CGNHCGYUESNHJH-HDJSIYSDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
366.9
MW (Da)
5.31
ALogP
3
HBA
1
HBD
63.1
PSA (Ų)
0.68
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 3',5'-cyclic-AMP phosphodiesterase 4D CHEMBL288 | IC50 | 7.52 | 7.52 | 30.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 3',5'-cyclic-AMP phosphodiesterase 4D | IC50 | = | 30.0 | nM | 7.52 | Inhibition of human PDE4D | 26288344 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26288344 | 10.1021/acs.jmedchem.5b00902 | No relevant target | 2 |
| 26288344 | 10.1021/acs.jmedchem.5b00902 | 3',5'-cyclic-AMP phosphodiesterase 4D | 1 |
Data from ChEMBL 36 via Core Engine