Compound Detail
CHEMBL362919
METHOXYCHLOR Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL362919 |
| Name | METHOXYCHLOR |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IAKOZHOLGAGEJT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
345.6
MW (Da)
5.21
ALogP
2
HBA
0
HBD
18.5
PSA (Ų)
0.71
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Androgen receptor CHEMBL3072 | IC50 | 4.55 | 4.55 | 28183.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Androgen receptor | IC50 | = | 28183.83 | nM | 4.55 | Inhibitory concentration against recombinant rat androgen receptor expressed in ... | 16134935 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18973326 | 10.1021/jm800337r | Nuclear receptor subfamily 1 group I member 3 | 40 |
| 16134935 | 10.1021/jm050403f | Androgen receptor | 1 |
| 18973326 | 10.1021/jm800337r | HEK293 | 1 |
| 12765240 | 10.1016/s0378-4274(02)00485-x | Multidrug resistance-associated protein 1 | 1 |
| 23571415 | 10.1124/mol.112.084152 | Solute carrier organic anion transporter family member 1B1 | 1 |
| 23571415 | 10.1124/mol.112.084152 | Solute carrier organic anion transporter family member 1B3 | 1 |
Data from ChEMBL 36 via Core Engine