Compound Detail
CHEMBL363308
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Basic Information
| ChEMBL ID | CHEMBL363308 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NZNYRZNCHUMSCE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
475.6
MW (Da)
5.94
ALogP
3
HBA
1
HBD
35.6
PSA (Ų)
0.34
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(4) dopamine receptor CHEMBL219 | Ki | 6.76 | 6.76 | 174.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(4) dopamine receptor | Ki | = | 174.5 | nM | 6.76 | In vitro ability to inhibit [3H]6b binding to human Dopamine receptor D4.4 | 15380206 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15380206 | 10.1016/j.bmcl.2004.07.068 | D(4) dopamine receptor | 3 |
Data from ChEMBL 36 via Core Engine