Compound Detail
CHEMBL364765
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL364765 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CHJHGFGTYYTUMH-HBNTYKKESA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
359.4
MW (Da)
1.11
ALogP
9
HBA
1
HBD
103.3
PSA (Ų)
0.63
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human alphaherpesvirus 2 CHEMBL370 | IC50 | 5.1 | 5.1 | 8000.0 | 1 |
| Human alphaherpesvirus 1 CHEMBL377 | IC50 | 5.1 | 5.1 | 8000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human alphaherpesvirus 1 | IC50 | = | 8000.0 | nM | 5.1 | Antiviral activity against Herpes simplex virus 1 | 19112024 |
| Human alphaherpesvirus 2 | IC50 | = | 8000.0 | nM | 5.1 | Antiviral activity against Herpes simplex virus 2 | 19112024 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15481985 | 10.1021/jm049806q | HEL | 6 |
| 15481985 | 10.1021/jm049806q | E6SM | 5 |
| 15481985 | 10.1021/jm049806q | ADMET | 2 |
| 19112024 | 10.1016/j.bmc.2008.11.075 | Human alphaherpesvirus 1 | 1 |
| 19112024 | 10.1016/j.bmc.2008.11.075 | Human alphaherpesvirus 2 | 1 |
Data from ChEMBL 36 via Core Engine