Compound Detail
CHEMBL3649505
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3649505 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DRBBILLFANXMKL-GZTJUZNOSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
391.4
MW (Da)
2.38
ALogP
9
HBA
2
HBD
112.7
PSA (Ų)
0.34
QED
0
Ro5 Violations
11
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.21
Ki 1 meas. best 7.02
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutaminyl-peptide cyclotransferase-like protein CHEMBL3638349 | Ki | 7.02 | 7.02 | 96.0 | 1 |
| Glutaminyl-peptide cyclotransferase-like protein CHEMBL3638349 | IC50 | 6.21 | 6.21 | 620.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutaminyl-peptide cyclotransferase-like protein | Ki | = | 96.0 | nM | 7.02 | Fluorometric Assay: All measurements were performed with a BioAssay Reader HTS-7... | - |
| Glutaminyl-peptide cyclotransferase-like protein | IC50 | = | 620.0 | nM | 6.21 | Fluorometric Assay: All measurements were performed with a BioAssay Reader HTS-7... | - |
Data from ChEMBL 36 via Core Engine