Compound Detail
CHEMBL3649517
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Basic Information
| ChEMBL ID | CHEMBL3649517 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GPQHOIQTHKOAGY-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
369.4
MW (Da)
3.39
ALogP
5
HBA
1
HBD
85.3
PSA (Ų)
0.27
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.37
Ki 1 meas. best 7.47
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutaminyl-peptide cyclotransferase-like protein CHEMBL3638349 | Ki | 7.47 | 7.47 | 34.0 | 1 |
| Glutaminyl-peptide cyclotransferase-like protein CHEMBL3638349 | IC50 | 6.37 | 6.37 | 430.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutaminyl-peptide cyclotransferase-like protein | Ki | = | 34.0 | nM | 7.47 | Fluorometric Assay: All measurements were performed with a BioAssay Reader HTS-7... | - |
| Glutaminyl-peptide cyclotransferase-like protein | IC50 | = | 430.0 | nM | 6.37 | Fluorometric Assay: All measurements were performed with a BioAssay Reader HTS-7... | - |
Data from ChEMBL 36 via Core Engine