Compound Detail
CHEMBL364953
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Basic Information
| ChEMBL ID | CHEMBL364953 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OLFSHHYOFRIMLB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
352.4
MW (Da)
2.53
ALogP
8
HBA
1
HBD
98.7
PSA (Ų)
0.55
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 1 CHEMBL4040 | Kd | 5.3 | 5.3 | 5000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 1 | Kd | = | 5000.0 | nM | 5.3 | Dissociation constant for ERK2 kinase | 15999996 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15999996 | 10.1021/jm0501174 | Mitogen-activated protein kinase 1 | 1 |
Data from ChEMBL 36 via Core Engine