Compound Detail
CHEMBL3655673
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Basic Information
| ChEMBL ID | CHEMBL3655673 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UCTJPSCONMENMI-WOJBJXKFSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
418.5
MW (Da)
5.52
ALogP
3
HBA
0
HBD
42.4
PSA (Ų)
0.55
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 10.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Orexin receptor type 2 CHEMBL1275216 | Ki | 10.1 | 10.1 | 0.1 | 1 |
| Orexin/Hypocretin receptor type 1 CHEMBL1075232 | Ki | 9.15 | 9.15 | 0.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Orexin receptor type 2 | Ki | = | 0.08 | nM | 10.1 | Radioligand Binding Assay: Radioligand binding assay described in Bergman et. al... | - |
| Orexin/Hypocretin receptor type 1 | Ki | = | 0.71 | nM | 9.15 | Radioligand Binding Assay: Radioligand binding assay described in Bergman et. al... | - |
Data from ChEMBL 36 via Core Engine