Compound Detail
CHEMBL3655678
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3655678 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AZVRNCHGYXJASK-HUUCEWRRSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
367.4
MW (Da)
4.02
ALogP
3
HBA
1
HBD
58.2
PSA (Ų)
0.76
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Orexin receptor type 2 CHEMBL1275216 | Ki | 8.0 | 8.0 | 10.0 | 1 |
| Orexin/Hypocretin receptor type 1 CHEMBL1075232 | Ki | 7.12 | 7.12 | 75.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Orexin receptor type 2 | Ki | = | 10.0 | nM | 8.0 | Radioligand Binding Assay: Radioligand binding assay described in Bergman et. al... | - |
| Orexin/Hypocretin receptor type 1 | Ki | = | 75.0 | nM | 7.12 | Radioligand Binding Assay: Radioligand binding assay described in Bergman et. al... | - |
Data from ChEMBL 36 via Core Engine