Compound Detail
CHEMBL3655713
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3655713 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZWJGMJZWOBLCCN-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
322.6
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.22
Ki 1 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Thioredoxin reductase CHEMBL3638339 | Ki | 6.6 | 6.6 | 250.0 | 1 |
| Thioredoxin reductase CHEMBL3638339 | IC50 | 5.22 | 5.22 | 6000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Thioredoxin reductase | Ki | = | 250.0 | nM | 6.6 | Inhibition Assay: All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2... | - |
| Thioredoxin reductase | IC50 | = | 6000.0 | nM | 5.22 | Inhibition Assay: All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2... | - |
Data from ChEMBL 36 via Core Engine