Compound Detail
CHEMBL3655714
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Basic Information
| ChEMBL ID | CHEMBL3655714 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RDQUTXFRRFEWDK-UHFFFAOYSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
318.2
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.12
Ki 1 meas. best 5.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Thioredoxin reductase CHEMBL3638339 | Ki | 5.92 | 5.92 | 1200.0 | 1 |
| Thioredoxin reductase CHEMBL3638339 | IC50 | 5.12 | 5.12 | 7500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Thioredoxin reductase | Ki | = | 1200.0 | nM | 5.92 | Inhibition Assay: All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2... | - |
| Thioredoxin reductase | IC50 | = | 7500.0 | nM | 5.12 | Inhibition Assay: All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2... | - |
Data from ChEMBL 36 via Core Engine