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Compound Detail

CHEMBL3655718

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CC(C)(C)n1[se]c2ccccc2c1=O

Basic Information

ChEMBL ID CHEMBL3655718
Phase Preclinical
Structure Type MOL
InChI Key ZKCKJYOYGUUURF-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

254.2
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H13NOSe
MW 254.19

Activity Summary

IC50 1 meas. best 4.82

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Thioredoxin reductase
CHEMBL3638339
IC50 4.82 4.82 15000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Thioredoxin reductase IC50 = 15000.0 nM 4.82 Inhibition Assay: All the benzisoselenazol-3(2H)-one and bisbenzisoselenazol-3(2... -

Data from ChEMBL 36 via Core Engine