Compound Detail
CHEMBL3665543
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Basic Information
| ChEMBL ID | CHEMBL3665543 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MWMKKJRCIMOWKJ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
431.6
MW (Da)
6.60
ALogP
4
HBA
1
HBD
51.3
PSA (Ų)
0.39
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 6.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| cGMP-dependent 3',5'-cyclic phosphodiesterase CHEMBL2652 | Ki | 6.96 | 6.96 | 110.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Ki | = | 110.0 | nM | 6.96 | Inhibition Assay: The activity of the compounds in accordance with the present i... | - |
| cGMP-dependent 3',5'-cyclic phosphodiesterase | Ki | = | 110.0 | nM | 6.96 | Inhibition Assay: The activity of the compounds in accordance with the present i... | - |
Data from ChEMBL 36 via Core Engine