Compound Detail
CHEMBL3667989
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Basic Information
| ChEMBL ID | CHEMBL3667989 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WYBNLHIHRKKQQO-CTYIDZIISA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
384.5
MW (Da)
3.19
ALogP
6
HBA
3
HBD
96.7
PSA (Ų)
0.64
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Activin receptor type-1-like CHEMBL5311 | IC50 | 6.91 | 6.84 | 124.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Activin receptor type-1-like | IC50 | = | 124.0 | nM | 6.91 | Radiometric Assay: ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was meas... | - |
| Activin receptor type-1-like | IC50 | = | 170.0 | nM | 6.77 | Flashplate Assay: In vitro enzyme inhibition using scintillation of incorporated... | - |
Data from ChEMBL 36 via Core Engine