Compound Detail
CHEMBL3667999
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Basic Information
| ChEMBL ID | CHEMBL3667999 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CETAVAHOOHFRIY-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
340.4
MW (Da)
1.92
ALogP
7
HBA
3
HBD
105.9
PSA (Ų)
0.66
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 8.92
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Activin receptor type-1-like CHEMBL5311 | IC50 | 8.92 | 8.6233 | 1.2 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Activin receptor type-1-like | IC50 | = | 1.2 | nM | 8.92 | Flashplate Assay: In vitro enzyme inhibition using scintillation of incorporated... | - |
| Activin receptor type-1-like | IC50 | = | 3.2 | nM | 8.49 | Flashplate Assay: In vitro enzyme inhibition using scintillation of incorporated... | - |
| Activin receptor type-1-like | IC50 | = | 3.5 | nM | 8.46 | Flashplate Assay: In vitro enzyme inhibition using scintillation of incorporated... | - |
Data from ChEMBL 36 via Core Engine