Compound Detail
CHEMBL3676153
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Basic Information
| ChEMBL ID | CHEMBL3676153 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MVTZRJHEQPXHNU-MRXNPFEDSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
390.8
MW (Da)
2.78
ALogP
3
HBA
4
HBD
115.7
PSA (Ų)
0.55
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 9.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Membrane metallo-endopeptidase-like 1 CHEMBL3638356 | IC50 | 9.1 | 9.1 | 0.8 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Membrane metallo-endopeptidase-like 1 | IC50 | = | 0.8 | nM | 9.1 | Inhibition Assay: Recombinant human neutral endopeptidase (expressed in insect c... | - |
| Membrane metallo-endopeptidase-like 1 | IC50 | = | 0.8 | nM | 9.1 | Inhibition Assay: Recombinant human neutral endopeptidase (expressed in insect c... | - |
Data from ChEMBL 36 via Core Engine