Compound Detail
CHEMBL368086
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Basic Information
| ChEMBL ID | CHEMBL368086 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JYERRXMRJUYTPA-UNOMPAQXSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
424.5
MW (Da)
4.74
ALogP
5
HBA
2
HBD
92.4
PSA (Ų)
0.46
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 9.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 9.0 | 9.0 | 1.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1.0 | nM | 9.0 | The compound was evaluated for the inhibition of [125I]- Angiotensin II (AII) bi... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(00)80691-5 | Oryctolagus cuniculus | 1 |
| - | 10.1016/S0960-894X(00)80691-5 | Unchecked | 1 |
| - | 10.1016/S0960-894X(00)80691-5 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine