Compound Detail
CHEMBL368923
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COC(=O)c1ccc(C(=O)OC)c2c(C(=O)c3ccc(Cn4c(C)nc5cnccc54)cc3)c[nH]c12
Basic Information
| ChEMBL ID | CHEMBL368923 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZNHBKGCJMBDLGW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
482.5
MW (Da)
4.07
ALogP
8
HBA
1
HBD
116.2
PSA (Ų)
0.29
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Platelet-activating factor receptor CHEMBL5136 | Ki | 8.54 | 8.54 | 2.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Platelet-activating factor receptor | Ki | = | 2.9 | nM | 8.54 | Binding potency against Platelet activating factor (PAF) receptor using [3H]C18-... | 9438024 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9438024 | 10.1021/jm970389+ | Platelet-activating factor receptor | 3 |
Data from ChEMBL 36 via Core Engine