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Compound Detail

CHEMBL3696108

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Cc1ccncc1-c1ccnc2c(-c3ccc(F)cc3)noc12

Basic Information

ChEMBL ID CHEMBL3696108
Phase Preclinical
Structure Type MOL
InChI Key GLTYDYPJPYPUJE-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

305.3
MW (Da)
4.40
ALogP
4
HBA
0
HBD
51.8
PSA (Ų)
0.55
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H12FN3O
MW 305.31
Aromatic Rings 4
Heavy Atoms 23
NP-Likeness -0.97

Activity Summary

IC50 2 meas. best 8.41

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Steroid 17-alpha-hydroxylase/17,20 lyase
CHEMBL3522
IC50 8.41 8.41 3.9 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine