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Compound Detail

CHEMBL3696115

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Cc1ccncc1-c1cccc2c(OCc3ccc(Cl)cc3)noc12

Basic Information

ChEMBL ID CHEMBL3696115
Phase Preclinical
Structure Type MOL
InChI Key SCOWBUGNRMASSY-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

350.8
MW (Da)
5.43
ALogP
4
HBA
0
HBD
48.1
PSA (Ų)
0.49
QED
1
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C20H15ClN2O2
MW 350.81
Aromatic Rings 4
Heavy Atoms 25
NP-Likeness -0.86

Activity Summary

IC50 2 meas. best 6.6

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Steroid 17-alpha-hydroxylase/17,20 lyase
CHEMBL3522
IC50 6.6 6.6 251.0 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine