Compound Detail
CHEMBL371391
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Basic Information
| ChEMBL ID | CHEMBL371391 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IDWNTTNNMPLDJW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
322.3
MW (Da)
2.88
ALogP
8
HBA
1
HBD
104.9
PSA (Ų)
0.62
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ribosomal protein S6 kinase alpha-5 CHEMBL4237 | IC50 | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ribosomal protein S6 kinase alpha-5 | IC50 | = | 10000.0 | nM | 5.0 | Inhibitory concentration against MSK-1 | 15955699 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15955699 | 10.1016/j.bmcl.2005.05.020 | Unchecked | 2 |
| 15955699 | 10.1016/j.bmcl.2005.05.020 | Ribosomal protein S6 kinase alpha-5 | 1 |
Data from ChEMBL 36 via Core Engine