Compound Detail
CHEMBL375913
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Basic Information
| ChEMBL ID | CHEMBL375913 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GIJBOCHXNWQHOY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
246.7
MW (Da)
1.42
ALogP
3
HBA
1
HBD
49.4
PSA (Ų)
0.82
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 4.55 | 4.55 | 28000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 28000.0 | nM | 4.55 | Activity at Wistar rat cortex AMPA receptor expressed in Xenopus laevis oocytes ... | 17552506 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17552506 | 10.1021/jm070120i | Unchecked | 4 |
| 18980844 | 10.1016/j.bmc.2008.10.036 | Unchecked | 3 |
| 20108934 | 10.1021/jm901495t | Oocyte | 2 |
| 17552506 | 10.1021/jm070120i | Hippocampus | 1 |
| 20108934 | 10.1021/jm901495t | No relevant target | 1 |
| 20108934 | 10.1021/jm901495t | Liver microsomes | 1 |
Data from ChEMBL 36 via Core Engine