Compound Detail
CHEMBL3764889
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Basic Information
| ChEMBL ID | CHEMBL3764889 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YHIMCTPOEPIBAR-UHFFFAOYSA-N |
| Parent Compound | CHEMBL3765872 |
| Active Moiety | CHEMBL3765872 |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
391.5
MW (Da)
4.16
ALogP
4
HBA
0
HBD
45.5
PSA (Ų)
0.59
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 5.63
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 CHEMBL3155 | Ki | 5.63 | 5.63 | 2336.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | Ki | = | 2344.23 | nM | 5.63 | Displacement of [3H]LSD from 5-HT7 receptor (unknown origin) expressed in CHO-K1... | 26852005 |
| 5-hydroxytryptamine receptor 7 | Ki | = | 2336.0 | nM | 5.63 | Displacement of [3H]LSD from 5-HT7 receptor (unknown origin) expressed in CHO-K1... | 26852005 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 26852005 | 10.1016/j.ejmech.2016.01.043 | 5-hydroxytryptamine receptor 7 | 2 |
Data from ChEMBL 36 via Core Engine