Compound Detail
CHEMBL377036
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL377036 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | STNCEVMLMPRGQU-HNNXBMFYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
269.4
MW (Da)
1.99
ALogP
2
HBA
2
HBD
48.1
PSA (Ų)
0.88
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 6.26 | 6.26 | 550.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 550.0 | nM | 6.26 | Activity at alpha7-5HT3 chimera expressed in SHEP1 cells by FLIPR assay | 16821801 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16821801 | 10.1021/jm0602413 | Liver microsomes | 1 |
| 16821801 | 10.1021/jm0602413 | Neuronal acetylcholine receptor subunit alpha-7 | 1 |
| 16821801 | 10.1021/jm0602413 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine