Compound Detail
CHEMBL381669
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C[C@H](NS(C)(=O)=O)c1ccc(Cc2ccc(OC(F)(F)F)cc2S(=O)(=O)c2ccccc2F)cc1
Basic Information
| ChEMBL ID | CHEMBL381669 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KBJSJOIMBDWJON-HNNXBMFYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
531.5
MW (Da)
4.76
ALogP
5
HBA
1
HBD
89.5
PSA (Ų)
0.42
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 2 CHEMBL253 | Ki | 9.4 | 9.4 | 0.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 2 | Ki | = | 0.4 | nM | 9.4 | Inhibition constant against Cannabinoid receptor 2 | 16115769 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16115769 | 10.1016/j.bmcl.2005.07.023 | Cannabinoid receptor 2 | 1 |
| 16115769 | 10.1016/j.bmcl.2005.07.023 | Cannabinoid receptor | 1 |
Data from ChEMBL 36 via Core Engine