Compound Detail
CHEMBL3819258
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3819258 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XBSUEIUGYQBZKL-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
410.9
MW (Da)
4.89
ALogP
6
HBA
2
HBD
66.0
PSA (Ų)
0.54
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 8.22 | 8.01 | 6.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 6.0 | nM | 8.22 | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D6 b... | - |
| Plasmodium falciparum | IC50 | = | 16.0 | nM | 7.8 | Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum W2 b... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C6MD00084C | Plasmodium falciparum | 2 |
Data from ChEMBL 36 via Core Engine