Compound Detail
CHEMBL382170
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Basic Information
| ChEMBL ID | CHEMBL382170 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CTBVBLUYSQJGIV-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
283.2
MW (Da)
1.22
ALogP
8
HBA
3
HBD
146.7
PSA (Ų)
0.56
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 7.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RNA-directed RNA polymerase CHEMBL4296320 | IC50 | 7.19 | 6.51 | 65.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RNA-directed RNA polymerase | IC50 | = | 65.0 | nM | 7.19 | Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving man... | 16509585 |
| RNA-directed RNA polymerase | IC50 | = | 680.0 | nM | 6.17 | Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase | 16509585 |
| RNA-directed RNA polymerase | IC50 | = | 680.0 | nM | 6.17 | Inhibitory activity against HCV 1b BK NS5B deltaC55 RNA polymerase involving mag... | 16509585 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 16509585 | 10.1021/jm051064t | RNA-directed RNA polymerase | 3 |
| 16509585 | 10.1021/jm051064t | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine